Mueller matrix microscope

Our new Mueller matrix microscope prototype

  • High sensitivity and repeatability in distinguishing specific, low-level Mueller Matrix elements.
  • Simultaneous measurement of 12 Mueller matrix elements within a rapid timeframe of less than 3 seconds, catering to dynamic applications.
  • Real-time measurement capabilities operating at video-rate speed, specifically capturing 2 Mueller Matrix elements for linear birefringence assessments, covering both magnitude and orientation.
  • Custom algebraic algorithm to reconstruct the full 16 MM elements from the 12 measured MM elements (in the absence of depolarization)
  • Adjustable to different wavelengths (VIS and NIR)
  • Software packages with data analysis features for all 6 polarization parameters (linear retardation – magnitude and angle; circular retardation – magnitude; linear diattenuation – magnitude and angle; and circular diattenuation – magnitude).
  • Optimal optical and polarimetric design engineered for cost efficiency without compromising on performance.
  • Highly customizable layout.


Film of biofilaments from cytoskeleton proteins. Self-propelled system.

Intensity imaging (what a normal microscope can see)


Live-birefrigence magnitude imaging (what our microscope can measure in real-time)

We usually report birefringence values in radians but they can be easily converted to nm. In this case, the 0.08 radians shown in the scale are equivalent to 7 nm of birefringence: 0.08*550 nm/(2*pi).

Full MM in a growing crystal

The optical layout is very flexible to accommodate different different types of in-situ experiments.  This is a photo of our prototype doing measurements in  microfluidic chambers